Breathing Ozonated Oil (BOO) - How To Support Your Airways

Ozone Therapy Made Easy

Most people who find this page already know something about the benefits of ozone therapy and the science behind it. Breathing Ozonated Oil - usually shortened to BOO - is one of the protocols people ask us about most, and it is also the one most often misunderstood.

Ozone gas must never be inhaled directly. Ozone is a lung irritant, and breathing it straight from a generator can cause real harm. BOO exists precisely because of that. By bubbling ozone slowly through a vegetable oil first, the ozone reacts with the oil rather than with your lungs, and what comes off the top of the flask is the vapour above the reacted oil, carrying ozonides and other products of that reaction. That is what you breathe.

Understanding that distinction is the whole point of this guide.

How can Breathing Ozonated Oil help?

People use BOO as a complementary therapy to support their respiratory comfort and general wellbeing. It is one of the gentler protocols to perform, and it needs no more equipment than an oil bubbler and the ozone generator you already own.

Please note: Natural Ozone does not claim that this protocol will cure any condition. Ozone therapy is best understood as complementary and adjuvant - something used alongside conventional care rather than instead of it. There is a wealth of scientific data you can explore in our study library, and we always recommend you follow the advice of your chosen health practitioner.

Watch the video

This video covers what BOO is, the equipment you need, and how to set it up safely at home.

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Why bubble ozone through oil?

Ozone gas is highly unstable - it breaks down within minutes, and it is an irritant to the lining of the airways. Vegetable oils are rich in unsaturated fatty acids, and those fatty acids have double bonds that ozone reacts with readily.

When ozone is bubbled slowly through oil in a sealed flask, it is consumed by that reaction. The vapour that rises above the oil carries ozonides and other products of that reaction. This is why the oil is not optional and not merely a filter - it is the chemistry that makes the protocol possible.

It is also why the equipment matters. A one-way check valve stops oil being drawn back into your generator, and the flask must not be overfilled or oil can carry over into the tubing.

What the research actually shows

There is one published clinical trial of ozone delivered through olive oil. Dengiz and colleagues, in Medical Gas Research in 2022, randomised 30 hospitalised patients in Istanbul - 15 given ozone alongside standard care, 15 given standard care alone. Ozone at 0.2 ppm was bubbled through a glass reservoir of olive oil, combined with cold water vapour, and delivered by mask for 10 minutes, three times a day, for five days. The ozone group had a shorter average hospital stay and a higher rate of negative PCR tests at day five.

You should have the limitations as well as the result. Thirty patients is a small trial, and the authors state plainly that they did no power analysis. Patients were not blinded and there was no sham treatment. Side effects were not systematically recorded. The generator was made by a pharmaceutical company that holds its patent. The setting was a hospital ward under medical supervision, not a home. The apparatus was also not quite the one you have - it added a water-vapour stage and used a mask rather than a nasal cannula.

Beyond that one trial there is nothing. We searched the published literature, including in Spanish, Italian, Turkish and Russian, and found no other human study of breathing ozonated oil - no case series, no observational study, nothing. The Madrid Declaration does not mention the protocol at all.

That is the honest position, and we would rather you had it from us than found it out later.

Dengiz E, Özcan Ç, Güven Yİ, et al. Ozone gas applied through nebulization as adjuvant treatment for lung respiratory diseases due to COVID-19 infections: a prospective randomized trial. Med Gas Res. 2022;12(2):55-59. PMID 34677153.
Sadowska J, Johansson B, Johannessen E, et al. Characterization of ozonated vegetable oils by spectroscopic and chromatographic methods. Chem Phys Lipids. 2008;151(2):85-91. PMID 18023273.

Equipment you will need

• Natural Ozone Home Ozone Therapy Protocol Handbook - included free with every ozone therapy bundle. This is where you will find the concentration, session length and frequency for BOO
• An oxygen supply - either an oxygen concentrator or a bottle with a low flow regulator
• OZONODE medical ozone generator
• Glass oil bubbler with diffuser straw, one-way check valve, silicone tubing and nasal cannula
• A carrier oil - olive oil or sunflower oil are the usual choices

All of this is included in our Biohackers Toolkit and Ozone Enthusiast bundles.

Setting up at home

1. Fill the glass flask with your carrier oil. Do not exceed 200 ml - overfilling risks oil carrying over into the tubing
2. Connect your oxygen supply to the O2 inlet at the back of the OZONODE. If this is your first time, see our guides for oxygen concentrators or oxygen tanks
3. Run the silicone tubing from the generator's ozone outlet to the diffuser inlet at the base of the flask
4. Fit the one-way check valve between the generator and the flask. This prevents oil being drawn back into your generator, which would damage it
5. Attach the nasal cannula to the outlet tube at the top of the flask
6. Set the concentration and flow rate as set out in your Protocol Handbook, and allow the generator a moment to settle
7. Breathe gently and normally through the cannula. There is nothing to be gained from breathing deeply or forcefully
8. When finished, switch off the generator and turn off the oxygen supply

Concentrations, session durations and how often to repeat are set out in the printed Protocol Handbook that comes with every bundle. They are not published here, because the right settings depend on the protocol and on the person.

Safety and contraindications

• Never breathe ozone gas directly from the generator. The oil is the only thing between the generator and your lungs. Never bypass it, and never run it past the point where the oil is spent
• Always fit the one-way check valve, and never fill the flask beyond 200 ml
• Start with a short session at a low setting and build up gradually only if you feel the therapy is helping
• Stop if you experience coughing, chest tightness, wheezing or any irritation of the airways
• Change the oil before it is spent. The oil is consumed by the reaction. Harshness, throat dryness or irritation partway through a session usually means the oil is saturated - stop, and replace it with fresh oil
• If you have a diagnosed respiratory condition such as asthma or COPD, speak to your doctor before starting. Do not use BOO in place of prescribed medication or an inhaler
• Check the tubing and valve before each session, and replace anything that is discoloured or perished

For more information

If you have questions, visit naturalozone.co.nz, send us a message or give us a call. We are a service-oriented Kiwi business and always happy to give advice and support.

See you in the next video.