Ozone therapy: a potential therapeutic adjunct for improving female reproductive health

Type: Literature review

Author:  Zaher Merhi1, 2, *, Bhavika Garg2, Rajean Moseley-LaRue3, Amber Ray Moseley3, André Hugo Smith3, John Zhang2


The current literature showed that most of the studies to date were performed on animal models and that there is a critical need to assess the effect of ozone, administered safely and particularly given transdermally and vaginally, on female reproduction (Figure 2). Future studies should be prospective in nature and should assess the impact of ozone therapy on oocyte quality and quantity in women undergoing fertility treatment, especially those who had poor prognosis due to low ovarian reserve.

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