Oxygen–Ozone Therapy in the Rehabilitation Field State of the Art on Mechanisms of Action, Safety and Effectiveness in Patients with Musculoskeletal Disorders

Type: Literature review

Author:  Alessandro de Sire 1,* , Francesco Agostini 2 , Lorenzo Lippi 3 , Massimiliano Mangone 2, Simone Marchese 2,


In this scenario, O2O3 therapy might be considered as a promising conservative and mini-invasive intervention with an active role, both alone or in combination with other treatments, in order to reduce pain and improve functioning in patients affected by musculoskeletal disorders.

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