Effectiveness of topical ozonated oil in severe osteoarthritis

Type: Randomised, triple-blinded, placebo controlled trial

Author: Ana Paula Anzolin aDiego da Silva Collares bRenato Tadeu dos Santos bAdriano Pasqualotti aLuciana Grazziotin Rossato-Grando cCharise Dallazem Bertol 


Pain relief was observed in all groups except in the placebo group where patients are diagnosed with severe osteoarthritis (degree 4) (p-value treatment and placebo group: 0.021 and 0.345, respectively).  For the first time, the pain relief in patients with severe osteoarthritis was demonstrated by the use of topical ozonated oil.

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