Basic biological and therapeutic effects of ozone Therapy in human medicine
Type: Book extract
Author: E. Borrelli
Department of Surgery and Bioengineering, Postgraduate Course of Ozonetherapy,
University of Siena, Italy
- Bocci
Department of Physiology, University of Siena, Italy
Summary:
In this chapter we will expose the biochemical and pharmacological mechanism of
action of ozone when dissolved in biological fluids. Although ozone is a strong oxidant,
under controlled conditions, it can be therapeutically useful, in several human diseases.
In fact ozone, once dissolved in the water or the blood, triggers a cascade of welldefined
chemical compounds acting on multiple cellular targets. We will demonstrate
that ozone is an extremely versatile drug and the therapeutic range has been defined
precisely to avoid any acute and chronic toxicity. An interesting aspect is that prolonged
ozone therapy allows an upregulation of the antioxidant enzymes and therefore ozone
therapy represents a system for correcting the chronic oxidative stress present in many
diseases.