Unlocking the Power of Ozonated Glycerine: Benefits, Uses, and Warnings

In the world of natural wellness and alternative therapies, ozonated glycerine (also known as ozonized glycerin or OG) is gaining attention for its unique properties. Created by infusing ozone gas into glycerine, this compound forms stable peroxides that deliver antimicrobial, anti-inflammatory, and oxidative benefits. Unlike free ozone, which can be irritating if breathed, ozonated glycerine offers a more stable delivery method with a longer half-life - up to 18 months when refrigerated. While research is still emerging, studies suggest it holds promise for various applications, from skincare to wound healing. However, it's essential to approach it with caution, as not all uses are fully supported by large-scale clinical trials, and potential side effects exist. Always consult a healthcare professional before trying it, especially for internal or inhalation methods.

In this article, we will explore the main benefits and uses of ozonated glycerine, backed by research where available, and highlight key warnings to ensure safe exploration.

Topical Application for Wound Healing and Skin Health

One of the most well-researched uses of ozonated glycerine is as a topical agent for promoting wound healing and treating skin conditions. Its antimicrobial properties help combat bacteria, viruses, and fungi, while its humectant (moisturising) nature (from the glycerine base) keeps the skin moisturized, aiding in faster recovery.

For instance, studies have shown that ozonated oils, including glycerine-based formulations, can accelerate cutaneous wound healing by reducing inflammation and enhancing tissue regeneration.

Users report success with conditions like cuts, burns, acne, eczema, psoriasis, fungal infections, and even herpes outbreaks. Early dental research from 2004 highlighted its bacteria-reducing effects in wound care, aligning with broader antimicrobial studies.

Warning: While generally safe for skin, excessive use may cause irritation. Patch test first, and avoid open wounds if you're sensitive to oxidants. Not all formulations are equal - opt for high-quality, lab-tested products such as Amazing Natural Ozone Glycerin Healing Gel.

Skincare and Anti-Aging Benefits

Ozonated Glycerin

Ozonated glycerine shines in cosmetics, where it acts as a hydrator and pigmentation reducer. Research indicates it can lighten age spots by decreasing melanin content in the skin. In this clinical study, formulations with 80 - 800 ppm OG applied daily for 8 weeks significantly reduced melanin levels without adverse effects. This makes it a gentle alternative for anti-aging routines, potentially improving skin tone, elasticity, and collagen production.

It's also valued for its anti-inflammatory and cytoprotective effects, which may help with overall skin rejuvenation. Some products incorporate it into creams for daily use, emphasising its role in tackling dark spots through ozone's oxidative power combined with glycerine's soothing properties.

Warning: Though studies report no toxicity at tested doses, avoid eye contact or use on sensitive areas without dilution. Long-term effects on skin microbiome are understudied, so monitor for any changes.

Nebulisation for Respiratory Support

Nebulising ozonated glycerine - diluting it (e.g., 5-30% with distilled water) and inhaling via a compressor type nebulizer - is an experimental method for delivering therapeutic ozonides to the lungs, allowing the benefits to be slowly released into the body. Proponents claim it helps with respiratory infections, inflammation, and viral recovery, such as from COVID-19 or mycobacterium. This study on ozone inhalation suggested it could reduce pneumonia rates in COVID-19 patients by disinfecting lung tissue.

Its stability allows for potential antioxidant boosts in the body, lasting 2-4 weeks internally.

Warning: This lacks extensive safety data. More research is needed to confirm benefits and risks.

Oral Ingestion and Gargling for Internal Wellness

Taken orally by mixing into liquids, ozonated glycerine may support gut health, immune function, and systemic healing. As a gargle or mouthwash, it addresses sore throats, oral infections, and post-dental care, with antimicrobial effects reducing bacteria without staining like chlorhexidine.

Studies on ozonated compounds show inactivation of viruses like SARS-CoV-2, suggesting potential for oral hygiene.

Warning: Small doses are key to avoid stomach upset, cramps, gas, or diarrhoea. Excessive intake could disrupt gut microbiome or mucosal linings. Not recommended for pregnant individuals or those with dehydration risks, as glycerine reduces body water.

Dental Applications for Oral Health

Ozonated glycerine is emerging as a powerful tool in dentistry, particularly for its antimicrobial properties. Applied via irrigation or directly to affected areas, it can support post-dental procedure recovery, reduce bacterial load in gum infections, and promote healing after extractions. Early research from 2004 demonstrated its effectiveness in reducing bacteria in oral wounds, making it a promising adjunct in dental care. Its use in veterinary dentistry also shows success in treating oral diseases in pets, suggesting potential for human applications.

As a rinse or gel, it may help manage gingivitis or periodontitis by targeting pathogens without the staining associated with traditional antiseptics like chlorhexidine.

Warning: Dental use should be guided by a dentist, as improper application may irritate sensitive oral tissues. Avoid swallowing during irrigation, and ensure proper dilution to prevent mucosal discomfort.

Other Emerging Uses: From Nasal Sprays to Veterinary Care

Ozonated glycerine is also explored for nasal/sinus sprays to clear infections, rectal enemas for gut detox, intravenous infusions for oxygenation and cancer support, and even veterinary applications for pet wounds or joint issues. Musculoskeletal benefits include potential relief for osteoarthritis through topical application.

For ocular use (eyedrops), it's highly diluted for infections, but evidence is limited.

Warning: Intravenous or enema methods require professional administration due to risks like cramping or Herxheimer reactions (temporary worsening from toxin release). Eye use demands extreme caution to avoid irritation. Veterinary uses should involve a vet.

Conclusion: A Promising Tool with Prudent Use

Ozonated glycerine offers exciting potential as "ozone therapy in a bottle," blending ozone's power with glycerine's safety for diverse benefits. From enhancing skin health to supporting respiratory and internal wellness, emerging research paints a positive picture. However, it's not a miracle cure - many applications are experimental, and side effects like irritation or dizziness can occur. Prioritize quality products, start low, and seek medical advice, especially for internal uses. As research evolves, ozonated glycerine could become a staple in natural health kits - stay informed and safe!