Ozonized glycerin based cosmetic products lighten age spots on human facial skin

Type: Clinical Trial

Author: Keigo Hanada ¹, Daiki Okuda ¹, Ryuhei Ogi ¹, Sayaka Kojima ¹, Risa Tsuruoka ¹, Gotaro Shiota ¹

Summary

In clinical study for the evaluation of effects of OG formulations on age spots on facial skin, 48 women were measured for the melanin content of them by a Mexameter at 4 and 8 weeks after daily twice application of OG formulations. Adverse events were monitored during the study.

Number of subjects with a decrease in melanin index from baseline to 4 or 8 weeks increased in both OG formulations 80 and 800 ppm, especially prominent at 8 weeks. There were no adverse events related to treatments of OG 80 and 800 ppm during the study.

The result indicated that applications of OG formulations are safe and effective in lightening age spots on the facial skin.

Link to paper