Therapeutic Treatment of Superoxide Dismutase 1 (G93A) Amyotrophic Lateral Sclerosis Model Mice with Medical Ozone Decelerates Trigeminal Motor Neuron Degeneration, Attenuates Microglial Proliferation, and Preserves Monocyte Levels

Type: Model mice study

Author:  Michael Bette 1,* , Eileen Cors 1,2,†, Carolin Kresse 1,† and Burkhard Schütz


Given that the currently available ALS drugs, riluzole and edaravone, only show modest beneficial effects in patients, additional treatment options are needed. We believe that medical ozone, if properly formulated and the best route of application determined could serve as a simple, low-cost adjunct therapy for ALS.

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