Modulating the Gut Microbiota via Rectal Ozone Insufflation in Gynecological Cancer Patients with Radiotherapy/ Chemotherapy-Induced Pelvic Toxicity: A Proposed Clinical Study Protocol
Type: Proposed Clinical Study Protocol
Author:Bernardino Clavo , Elizabeth Córdoba-Lanús, Gregorio Martínez-Sánchez, Mario Federico , Ángeles Cánovas-Molina, José E. Piñero, Ana M. Vargas-Prad Avinash
Summary
This forward-thinking protocol outlines how rectal ozone insufflation could help cancer patients dealing with long-term pelvic side effects from radiotherapy and chemotherapy. It highlights ozone's potential to support gut microbiota balance, reduce inflammation, and strengthen the intestinal barrier through natural pathways like Nrf2 activation. For home users interested in rectal insufflation (using safe, properly generated ozone mixtures), this points to exciting possibilities for promoting overall gut health and comfort.