Daily Oxygen O3 Treatment Reduces Muscular Fatigue and Improves Cardiac Performance in Rats Subjected to Prolonged High Intensity Physical Exercise

Type: Animal model trial

Author:  C. Di Filippo, 1 M. C. Trotta, 1 R. Maisto, 1 D. Siniscalco, 1 M. Luongo, 2 L. Mascolo, 2 R. Alfano, 2 M. Accardo, 3


In conclusion, daily i.p. ozone treatment reduces the muscular fatigue and improves cardiac performance in rats subjected to prolonged high intensity exercise. This was exerted through improvement of NO bioavailability and reduction of oxidative stress to gastrocnemius muscle and to the heart.

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