Clinical Uses and Molecular Aspects of Ozone Therapy:

Type: Literature review                

Author: Ana Paula Pivotto, Fernanda Weyand Banhuk, Izabela Virginia Staffen, Maiara Aline Daga, Thaís Soprani Ayala and Rafael Andrade Menolli


Extensive studies have shown ozone’s effects, as well as the safety of its application in various modalities of use. Other studies showed its toxicity, which depends on the doses of use. Emerging evidence revealed that ozone also plays an important role in the wound healing and modulation of immune cells, describing the molecular pathways responsible for these actions and describing therapeutic actions in the treatment of wounds, pain, postoperative and infectious diseases.

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